With over 10 years of experience, we have supported over 350+ clinical trials to decode the complete TME and move forward with confidence.
Spatial analysis services: unlock the full complexity of the tumor microenvironment
NeoGenomics is leading the future of spatial biology adoption in oncology clinical trials delivering cutting-edge, AI-driven image analysis, comprehensive spatial insights, and collaborative scientific leadership to drive deeper understanding of the tumor microenvironment (TME).
| ✓ Decode complex biology | ✓ Validate biomarkers & targets |
| ✓ Profile immune suppressive TME | ✓ Mechanism of action insights |
| ✓ Map co-expression & spatial relationships | ✓ Precision medicine initiatives |
Harness the scientific expertise and power of multiple platforms to unlock key insights and fast-track your therapeutic development.
Hyperplex analysis
Deep spatial insights, confidence in every decision
Paletrra,™ exclusively available from NeoGenomics, combines whole-tissue workflow, AI-driven image analysis, and advanced spatial analytics to deliver comprehensive TME insights without requiring end-user optimization. It enables profiling of up to 60+ protein biomarkers within a single tissue section, offering both multiplex and hyperplex options.
Backed by over a decade of expertise in Multiomyx™ cyclic immunofluorescence technology, Paletrra also enables RNA fluorescence in situ hybridization (ISH) on the same slide, delivering multi-omic measurements at the single-cell level.
Multiplex analysis
End-to-end Akoya PhenoImager™ and Bruker GeoMx™ Digital Spatial Profiler (DSP) Services
PhenoImager
Simultaneously detect 2-6 different markers from a single FFPE tissue slide streamlining low-order multiplex panel implementation workflow.
- Automated staining with Opal TSA-based amplification kit
- High-throughput whole-slide multispectral imaging with up to 6 markers and continuous loading of 80+ slides
- Fast turnaround time
- Integrated with RNAScope®
- Image Analysis by Indica HALO: single cell quantitative cellular classification, spatial analysis including nearest neighbors, and density heatmaps, combine analysis and results – specific compartment for same slide or serial slides.
GeoMx™ DSP
Combines standard immunofluorescence techniques with digital optical barcoding technology for morphologically guided, highly multiplexed, spatially resolved RNA, and protein tissue profiling.
- Whole transcriptome, cancer transcriptome and proteins profiling.
- Region-specific profiling to reduce noise and accelerate time to results.
- Detect low to high expressors with 5 logs of dynamic range.
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