PanTracer LBx is a liquid biopsy next‑generation sequencing panel for advanced‑stage pan‑solid tumor indications. The assay detects single nucleotide variants (SNVs), insertions/deletions (InDels), copy number variants (CNVs), and fusions across a comprehensive gene set, plus microsatellite instability (MSI‑High status) and blood tumor mutational burden (bTMB) score.
NGS (514 total genes: ctDNA analysis across 514 genes; fusion analysis across a subset of these genes), plus MSI and bTMB
NEO PanTracer LBx
- Next Generation Sequencing (NGS)
- Liquid Biopsy
- Epic Aura Integration
Specimen Requirements
Peripheral blood: two x 10 mL Streck Cell-Free DNA BCT® tubes
Storage and Transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Do not refrigerate or freeze the gel wrap.
CPT Code(s)*
81464
Turnaround time
7 Days
Level of Service
- Global
Integrations
- Epic Aura
New York Approved: No
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Biomarkers
DNA Sequencing
| SNVs + Indels | |||||
|---|---|---|---|---|---|
| ABL1 | ABL2 | ||||
| ABRAXAS1 | ACVR1 | ||||
| ACVR1B | ADGRA2 | ||||
| AKT1 | AKT2 | ||||
| AKT3 | ALK | ||||
| ALOX12B | AMER1 | ||||
| ANKRD11 | ANKRD26 | ||||
| APC | AR | ||||
| ARAF | ARFRP1 | ||||
| ARID1A | ARID1B | ||||
| ARID2 | ARID5B | ||||
| ASXL1 | ASXL2 | ||||
| ATM | ATR | ||||
| ATRX | AURKA | ||||
| AURKB | AXIN1 | ||||
| AXIN2 | AXL | ||||
| B2M | BAP1 | ||||
| BARD1 | BBC3 | ||||
| BCL10 | BCL2 | ||||
| BCL2L1 | BCL2L11 | ||||
| BCL2L2 | BCL6 | ||||
| BCOR | BCORL1 | ||||
| BCR | BIRC3 | ||||
| BLM | BMPR1A | ||||
| BRAF | BRCA1 | ||||
| BRCA2 | BRD4 | ||||
| BRIP1 | BTG1 | ||||
| BTK | CALR | ||||
| CARD11 | CASP8 | ||||
| CBFB | CBL | ||||
| CCN6 | CCND1 | ||||
| CCND2 | CCND3 | ||||
| CCNE1 | CD274 | ||||
| CD276 | CD74 | ||||
| CD79A | CD79B | ||||
| CDC73 | CDH1 | ||||
| CDK12 | CDK4 | ||||
| CDK6 | CDK8 | ||||
| CDKN1A | CDKN1B | ||||
| CDKN2A | CDKN2B | ||||
| CDKN2C | CEBPA | ||||
| CENPA | CHD2 | ||||
| CHD4 | CHEK1 | ||||
| CHEK2 | CIC | ||||
| COP1 | CREBBP | ||||
| CRKL | CRLF2 | ||||
| CSF1R | CSF3R | ||||
| CSNK1A1 | CTCF | ||||
| CTLA4 | CTNNA1 | ||||
| CTNNB1 | CUL3 | ||||
| CUX1 | CXCR4 | ||||
| CYLD | DAXX | ||||
| DCUN1D1 | DDR2 | ||||
| DDX41 | DHX15 | ||||
| DICER1 | DIS3 | ||||
| DNAJB1 | DNMT1 | ||||
| DNMT3A | DNMT3B | ||||
| DOT1L | E2F3 | ||||
| EED | EGFL7 | ||||
| EGFR | EIF1AX | ||||
| EIF4A2 | EIF4E | ||||
| ELOC | EML4 | ||||
| EMSY | EP300 | ||||
| EPCAM | EPHA3 | ||||
| EPHA5 | EPHA7 | ||||
| EPHB1 | ERBB2 | ||||
| ERBB3 | ERBB4 | ||||
| ERCC1 | ERCC2 | ||||
| ERCC3 | ERCC4 | ||||
| ERCC5 | ERG | ||||
| ERRFI1 | ESR1 | ||||
| ETS1 | ETV1 | ||||
| ETV4 | ETV5 | ||||
| ETV6 | EWSR1 | ||||
| EZH2 | FANCA | ||||
| FANCC | FANCD2 | ||||
| FANCE | FANCF | ||||
| FANCG | FANCI | ||||
| FANCL | FAS | ||||
| FAT1 | FBXW7 | ||||
| FGF1 | FGF10 | ||||
| FGF14 | FGF19 | ||||
| FGF2 | FGF23 | ||||
| FGF3 | FGF4 | ||||
| FGF5 | FGF6 | ||||
| FGF7 | FGF8 | ||||
| FGF9 | FGFR1 | ||||
| FGFR2 | FGFR3 | ||||
| FGFR4 | FH | ||||
| FLCN | FLI1 | ||||
| FLT1 | FLT3 | ||||
| FLT4 | FOXA1 | ||||
| FOXL2 | FOXO1 | ||||
| FOXP1 | FRS2 | ||||
| FUBP1 | FYN | ||||
| GABRA6 | GATA1 | ||||
| GATA2 | GATA3 | ||||
| GATA4 | GATA6 | ||||
| GEN1 | GID4 | ||||
| GLI1 | GNA11 | ||||
| GNA13 | GNAQ | ||||
| GNAS | GPS2 | ||||
| GREM1 | GRIN2A | ||||
| GRM3 | GSK3B | ||||
| H1-2 | H2BC5 | ||||
| H3-3A | H3-3B | ||||
| H3-4 | H3-5 | ||||
| H3C1 | H3C10 | ||||
| H3C11 | H3C12 | ||||
| H3C13 | H3C2 | ||||
| H3C3 | H3C4 | ||||
| H3C6 | H3C7 | ||||
| H3C8 | HGF | ||||
| HNF1A | HNRNPK | ||||
| HOXB13 | HRAS | ||||
| HSD3B1 | HSP90AA1 | ||||
| ICOSLG | ID3 | ||||
| IDH1 | IDH2 | ||||
| IFNGR1 | IGF1 | ||||
| IGF1R | IGF2 | ||||
| IKBKE | IKZF1 | ||||
| IL10 | IL7R | ||||
| INHA | INHBA | ||||
| INPP4A | INPP4B | ||||
| INSR | IRF2 | ||||
| IRF4 | IRS1 | ||||
| IRS2 | JAK1 | ||||
| JAK2 | JAK3 | ||||
| JUN | KAT6A | ||||
| KDM5A | KDM5C | ||||
| KDM6A | KDR | ||||
| KEAP1 | KEL | ||||
| KIF5B | KIT | ||||
| KLF4 | KLHL6 | ||||
| KRAS | LAMP1 | ||||
| LATS1 | LATS2 | ||||
| LMO1 | LRP1B | ||||
| LYN | LZTR1 | ||||
| MAGI2 | MALT1 | ||||
| MAP2K1 | MAP2K2 | ||||
| MAP2K4 | MAP3K1 | ||||
| MAP3K13 | MAP3K14 | ||||
| MAP3K4 | MAPK1 | ||||
| MAPK3 | MAX | ||||
| MCL1 | MDC1 | ||||
| MDM2 | MDM4 | ||||
| MED12 | MEF2B | ||||
| MEN1 | MET | ||||
| MGA | MITF | ||||
| MLH1 | MLL | ||||
| MLLT3 | MPL | ||||
| MRE11 | MSH2 | ||||
| MSH3 | MSH6 | ||||
| MST1 | MST1R | ||||
| MTOR | MUTYH | ||||
| MYB | MYC | ||||
| MYCL | MYCN | ||||
| MYD88 | MYOD1 | ||||
| NAB2 | NBN | ||||
| NCOA3 | NCOR1 | ||||
| NEGR1 | NF1 | ||||
| NF2 | NFE2L2 | ||||
| NFKBIA | NKX2-1 | ||||
| NKX3-1 | NOTCH1 | ||||
| NOTCH2 | NOTCH3 | ||||
| NOTCH4 | NPM1 | ||||
| NRAS | NRG1 | ||||
| NSD1 | NTRK1 | ||||
| NTRK2 | NTRK3 | ||||
| NUP93 | NUTM1 | ||||
| PAK1 | PAK3 | ||||
| PAK5 | PALB2 | ||||
| PARP1 | PAX3 | ||||
| PAX5 | PAX7 | ||||
| PAX8 | PBRM1 | ||||
| PDCD1 | PDCD1LG2 | ||||
| PDGFRA | PDGFRB | ||||
| PDK1 | PGR | ||||
| PHF6 | PHOX2B | ||||
| PIK3C2B | PIK3C2G | ||||
| PIK3C3 | PIK3CA | ||||
| PIK3CB | PIK3CD | ||||
| PIK3CG | PIK3R1 | ||||
| PIK3R2 | PIK3R3 | ||||
| PIM1 | PLCG2 | ||||
| PLK2 | PMAIP1 | ||||
| PMS1 | PMS2 | ||||
| PNRC1 | POLD1 | ||||
| POLE | PPARG | ||||
| PPM1D | PPP2R1A | ||||
| PPP2R2A | PPP6C | ||||
| PRDM1 | PREX2 | ||||
| PRKAR1A | PRKCI | ||||
| PRKDC | PRKN | ||||
| PRSS8 | PTCH1 | ||||
| PTEN | PTPN11 | ||||
| PTPRD | PTPRS | ||||
| PTPRT | QKI | ||||
| RAB35 | RAC1 | ||||
| RAD21 | RAD50 | ||||
| RAD51 | RAD51B | ||||
| RAD51C | RAD51D | ||||
| RAD52 | RAD54L | ||||
| RAF1 | RANBP2 | ||||
| RARA | RASA1 | ||||
| RB1 | RBM10 | ||||
| RECQL4 | REL | ||||
| RET | RHEB | ||||
| RHOA | RICTOR | ||||
| RIT1 | RNF43 | ||||
| ROS1 | RPS6KA4 | ||||
| RPS6KB1 | RPS6KB2 | ||||
| RPTOR | RUNX1 | ||||
| RUNX1T1 | RYBP | ||||
| SDHA | SDHAF2 | ||||
| SDHB | SDHC | ||||
| SDHD | SETBP1 | ||||
| SETD2 | SF3B1 | ||||
| SH2B3 | SH2D1A | ||||
| SHQ1 | SLIT2 | ||||
| SLX4 | SMAD2 | ||||
| SMAD3 | SMAD4 | ||||
| SMARCA4 | SMARCB1 | ||||
| SMARCD1 | SMC1A | ||||
| SMC3 | SMO | ||||
| SNCAIP | SOCS1 | ||||
| SOX10 | SOX17 | ||||
| SOX2 | SOX9 | ||||
| SPEN | SPOP | ||||
| SPTA1 | SRC | ||||
| SRSF2 | STAG1 | ||||
| STAG2 | STAT3 | ||||
| STAT4 | STAT5A | ||||
| STAT5B | STK11 | ||||
| STK40 | SUFU | ||||
| SUZ12 | SYK | ||||
| TAF1 | TBX3 | ||||
| TCF3 | TCF7L2 | ||||
| TENT5C | TERC | ||||
| TERT Promoter | TET1 | ||||
| TET2 | TFE3 | ||||
| TFRC | TGFBR1 | ||||
| TGFBR2 | TMEM127 | ||||
| TMPRSS2 | TNFAIP3 | ||||
| TNFRSF14 | TOP1 | ||||
| TOP2A | TP53 | ||||
| TP63 | TRAF2 | ||||
| TRAF7 | TSC1 | ||||
| TSC2 | TSHR | ||||
| U2AF1 | VEGFA | ||||
| VHL | VTCN1 | ||||
| WT1 | XIAP | ||||
| XPO1 | XRCC2 | ||||
| YAP1 | YES1 | ||||
| ZBTB2 | ZBTB7A | ||||
| ZFHX3 | ZNF217 | ||||
| ZNF703 | ZRSR2 | ||||
| CNVs | |||||
|---|---|---|---|---|---|
| AKT2 | ALK | AR | ATM | BRAF | BRCA1 |
| BRCA2 | CCND1 | CCND3 | CCNE1 | CDK4 | CDK6 |
| CHEK1 | CHEK2 | EGFR | ERBB2 | ERBB3 | ERCC1 |
| ERCC2 | ESR1 | FGF1 | FGF10 | FGF14 | FGF19 |
| FGF2 | FGF23 | FGF3 | FGF4 | FGF5 | FGF6 |
| FGF7 | FGF8 | FGF9 | FGFR1 | FGFR2 | FGFR3 |
| FGFR4 | JAK2 | KIT | KRAS | LAMP1 | MDM2 |
| MDM4 | MET | MYC | MYCL | MYCN | NRAS |
| NRG1 | PDGFRA | PDGFRB | PIK3CA | PIK3CB | PTEN |
| RAF1 | RET | RICTOR | RPS6KB1 | TFRC | |
| Genomic Signatures | |||||
|---|---|---|---|---|---|
| MSI | TMB | ||||
| Fusions | |||||
|---|---|---|---|---|---|
| ABL1 | ALK | BCR | BRAF | CD74 | EGFR |
| ETV1 | ETV4 | ETV6 | EWSR1 | FGFR2 | FGFR3 |
| NAB2 | NTRK1 | NTRK2 | NUTM1 | PAX3 | PAX8 |
| PPARG | RET | ROS1 | TFE3 | TMPRSS2 | |
Last Updated: August 04, 2026