NEO PanTracer LBx

Next Generation Sequencing (NGS)
Liquid Biopsy
Epic Aura Integration

PanTracer LBx is a liquid biopsy next‑generation sequencing panel for advanced‑stage pan‑solid tumor indications. The assay detects single nucleotide variants (SNVs), insertions/deletions (InDels), copy number variants (CNVs), and fusions across a comprehensive gene set, plus microsatellite instability (MSI‑High status) and blood tumor mutational burden (bTMB) score.

NGS (514 total genes: ctDNA analysis across 514 genes; fusion analysis across a subset of these genes), plus MSI and bTMB

Specimen Requirements

Peripheral blood: two x 10 mL Streck Cell-Free DNA BCT® tubes

Storage and Transportation

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Do not refrigerate or freeze the gel wrap.

CPT Code(s)*

81464

Turnaround time

7 Days

Level of Service

Global

Integrations

Epic Aura

See all integrations →

New York Approved: No

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.

Biomarkers

DNA Sequencing

SNVs + Indels
ABL1	ABL2	ABRAXAS1	ACVR1	ACVR1B	ADGRA2
AKT1	AKT2	AKT3	ALK	ALOX12B	AMER1
ANKRD11	ANKRD26	APC	AR	ARAF	ARFRP1
ARID1A	ARID1B	ARID2	ARID5B	ASXL1	ASXL2
ATM	ATR	ATRX	AURKA	AURKB	AXIN1
AXIN2	AXL	B2M	BAP1	BARD1	BBC3
BCL10	BCL2	BCL2L1	BCL2L11	BCL2L2	BCL6
BCOR	BCORL1	BCR	BIRC3	BLM	BMPR1A
BRAF	BRCA1	BRCA2	BRD4	BRIP1	BTG1
BTK	CALR	CARD11	CASP8	CBFB	CBL
CCN6	CCND1	CCND2	CCND3	CCNE1	CD274
CD276	CD74	CD79A	CD79B	CDC73	CDH1
CDK12	CDK4	CDK6	CDK8	CDKN1A	CDKN1B
CDKN2A	CDKN2B	CDKN2C	CEBPA	CENPA	CHD2
CHD4	CHEK1	CHEK2	CIC	COP1	CREBBP
CRKL	CRLF2	CSF1R	CSF3R	CSNK1A1	CTCF
CTLA4	CTNNA1	CTNNB1	CUL3	CUX1	CXCR4
CYLD	DAXX	DCUN1D1	DDR2	DDX41	DHX15
DICER1	DIS3	DNAJB1	DNMT1	DNMT3A	DNMT3B
DOT1L	E2F3	EED	EGFL7	EGFR	EIF1AX
EIF4A2	EIF4E	ELOC	EML4	EMSY	EP300
EPCAM	EPHA3	EPHA5	EPHA7	EPHB1	ERBB2
ERBB3	ERBB4	ERCC1	ERCC2	ERCC3	ERCC4
ERCC5	ERG	ERRFI1	ESR1	ETS1	ETV1
ETV4	ETV5	ETV6	EWSR1	EZH2	FANCA
FANCC	FANCD2	FANCE	FANCF	FANCG	FANCI
FANCL	FAS	FAT1	FBXW7	FGF1	FGF10
FGF14	FGF19	FGF2	FGF23	FGF3	FGF4
FGF5	FGF6	FGF7	FGF8	FGF9	FGFR1
FGFR2	FGFR3	FGFR4	FH	FLCN	FLI1
FLT1	FLT3	FLT4	FOXA1	FOXL2	FOXO1
FOXP1	FRS2	FUBP1	FYN	GABRA6	GATA1
GATA2	GATA3	GATA4	GATA6	GEN1	GID4
GLI1	GNA11	GNA13	GNAQ	GNAS	GPS2
GREM1	GRIN2A	GRM3	GSK3B	H1-2	H2BC5
H3-3A	H3-3B	H3-4	H3-5	H3C1	H3C10
H3C11	H3C12	H3C13	H3C2	H3C3	H3C4
H3C6	H3C7	H3C8	HGF	HNF1A	HNRNPK
HOXB13	HRAS	HSD3B1	HSP90AA1	ICOSLG	ID3
IDH1	IDH2	IFNGR1	IGF1	IGF1R	IGF2
IKBKE	IKZF1	IL10	IL7R	INHA	INHBA
INPP4A	INPP4B	INSR	IRF2	IRF4	IRS1
IRS2	JAK1	JAK2	JAK3	JUN	KAT6A
KDM5A	KDM5C	KDM6A	KDR	KEAP1	KEL
KIF5B	KIT	KLF4	KLHL6	KMT2A	KRAS
LAMP1	LATS1	LATS2	LMO1	LRP1B	LYN
LZTR1	MAGI2	MALT1	MAP2K1	MAP2K2	MAP2K4
MAP3K1	MAP3K13	MAP3K14	MAP3K4	MAPK1	MAPK3
MAX	MCL1	MDC1	MDM2	MDM4	MED12
MEF2B	MEN1	MET	MGA	MITF	MLH1
MLLT3	MPL	MRE11	MSH2	MSH3	MSH6
MST1	MST1R	MTOR	MUTYH	MYB	MYC
MYCL	MYCN	MYD88	MYOD1	NAB2	NBN
NCOA3	NCOR1	NEGR1	NF1	NF2	NFE2L2
NFKBIA	NKX2-1	NKX3-1	NOTCH1	NOTCH2	NOTCH3
NOTCH4	NPM1	NRAS	NRG1	NSD1	NTRK1
NTRK2	NTRK3	NUP93	NUTM1	PAK1	PAK3
PAK5	PALB2	PARP1	PAX3	PAX5	PAX7
PAX8	PBRM1	PDCD1	PDCD1LG2	PDGFRA	PDGFRB
PDK1	PGR	PHF6	PHOX2B	PIK3C2B	PIK3C2G
PIK3C3	PIK3CA	PIK3CB	PIK3CD	PIK3CG	PIK3R1
PIK3R2	PIK3R3	PIM1	PLCG2	PLK2	PMAIP1
PMS1	PMS2	PNRC1	POLD1	POLE	PPARG
PPM1D	PPP2R1A	PPP2R2A	PPP6C	PRDM1	PREX2
PRKAR1A	PRKCI	PRKDC	PRKN	PRSS8	PTCH1
PTEN	PTPN11	PTPRD	PTPRS	PTPRT	QKI
RAB35	RAC1	RAD21	RAD50	RAD51	RAD51B
RAD51C	RAD51D	RAD52	RAD54L	RAF1	RANBP2
RARA	RASA1	RB1	RBM10	RECQL4	REL
RET	RHEB	RHOA	RICTOR	RIT1	RNF43
ROS1	RPS6KA4	RPS6KB1	RPS6KB2	RPTOR	RUNX1
RUNX1T1	RYBP	SDHA	SDHAF2	SDHB	SDHC
SDHD	SETBP1	SETD2	SF3B1	SH2B3	SH2D1A
SHQ1	SLIT2	SLX4	SMAD2	SMAD3	SMAD4
SMARCA4	SMARCB1	SMARCD1	SMC1A	SMC3	SMO
SNCAIP	SOCS1	SOX10	SOX17	SOX2	SOX9
SPEN	SPOP	SPTA1	SRC	SRSF2	STAG1
STAG2	STAT3	STAT4	STAT5A	STAT5B	STK11
STK40	SUFU	SUZ12	SYK	TAF1	TBX3
TCF3	TCF7L2	TENT5C	TERC	TERT	TET1
TET2	TFE3	TFRC	TGFBR1	TGFBR2	TMEM127
TMPRSS2	TNFAIP3	TNFRSF14	TOP1	TOP2A	TP53
TP63	TRAF2	TRAF7	TSC1	TSC2	TSHR
U2AF1	VEGFA	VHL	VTCN1	WT1	XIAP
XPO1	XRCC2	YAP1	YES1	ZBTB2	ZBTB7A
ZFHX3	ZNF217	ZNF703	ZRSR2

CNVs
AKT2	ALK	AR	ATM	BRAF	BRCA1
BRCA2	CCND1	CCND3	CCNE1	CDK4	CDK6
CHEK1	CHEK2	EGFR	ERBB2	ERBB3	ERCC1
ERCC2	ESR1	FGF1	FGF10	FGF14	FGF19
FGF2	FGF23	FGF3	FGF4	FGF5	FGF6
FGF7	FGF8	FGF9	FGFR1	FGFR2	FGFR3
FGFR4	JAK2	KIT	KRAS	LAMP1	MDM2
MDM4	MET	MYCL	MYCN	NRAS	NRG1
PDGFRA	PDGFRB	PIK3CA	PIK3CB	PTEN	RAF1
RET	RICTOR	RPS6KB1	TFRC

Genomic Signatures
MSI	TMB

Fusions
ABL1	ALK	BCR	BRAF	CD74	EGFR
ETV1	ETV4	ETV6	EWSR1	FGFR2	FGFR3
NAB2	NTRK1	NTRK2	NUTM1	PAX3	PAX8
PPARG	RET	ROS1	TFE3	TMPRSS2

Last Updated: June 19, 2026

Get in touch

Our Client Services team is on hand to help. Please call us at 866.776.5907, Option 3.