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The Sarcoma Comprehensive NGS Fusion Panel is an RNA-based next-generation sequencing panel that detects translocations and fusions with known and novel fusion partners of these genes: ACTB, AHRR, ALK, ASPSCR1, ATF1, ATIC, BCOR, BRAF, C11orf95, CAMTA1, CARS1, CCNB3, CDH11, CIC, CLTC, CNBP, COL1A1, COL1A2, CREB1, CREB3L1, CREB3L2, CSF1, CTNNB1, DDIT3, DUX4, EML4, EPC1, ERG, ETV1, ETV4, ETV6, EWSR1, FEV, FLI1, FOXO1, FRK, FUS, GLI1, HAS2, HEY1, HMGA2, IL2RB, ITK, JAZF1, LMNA, LPP, MEAF6, MRTFB, MYH9, MYLK, NAB2, NCOA1, NCOA2, NFATC2, NFIB, NR4A3, NTRK1, NTRK2, NTRK3, NUTM2A, NUTM2B, OMD, PAX3, PATZ1, PAX7, PBX1, PDGFB, PDGFRB, PHF1, PLAG1, POU5F1, RAD51B, RANBP2, ROS1, SEC31A, SRF, SS18, SSX1, SSX2, SSX4B, STAT6, SUZ12, SYK, TAF15, TCF12, TEAD1, TFE3, TFG, THRAP3, TPM3, TPM4, USP6, WT1, WWTR1, YAP1, YWHAE and ZNF444.
As of May 12, 2025, this test serves as replacement for the following test(s) that are no longer offered:
Ewing Sarcoma NGS Fusion Panel
NeoTYPE® Liposarcoma Fusion Profile
Non-Ewing Sarcoma NGS Fusion Panel
Rhabdomyosarcoma NGS Fusion Panel
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*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: July 28, 2025