KRAS Mutation Analysis by PCR

  • Molecular
The KRAS Mutation Analysis Assay is a real-time PCR-based assay designed to detect somatic mutations in exons 2, 3 and 4 of the KRAS gene. This assay is designed to detect the following KRAS mutations: Exon 2 - G12C, G12A/D/R/V/S and G13D; Exon 3 - A59E/G/T and Q61H/L/R; Exon 4 - K117N/R/E and A146T/P/V. Testing is available separately or in combination with BRAF, HRAS and NRAS in the RAS/RAF Panel.
Turnaround time
7 Days

Level of Service

  • Global
New York Approved: Yes

Specimen Requirements

FFPE solid tumor tissue: Paraffin block is preferred. Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.

Storage and Transportation

Storage & Transportation: Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

CPT Code(s)*

81275, 81276

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.

Last Updated: January 22, 2025

Get in touch

Our Client Services team is on hand to help. Please call us at 866.776.5907, Option 3.