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Low-Grade/Small B-Cell Lymphoma FISH Panel
- FISH
Probes: BCL6 (3q27) | CCND1/IgH t(11;14) IgH/BCL2 t(14;18) | MALT1 (18q21)
Probes may be ordered separately.
Disease(s): NHL, B-Cell Lymphoma, MCL, follicular lymphoma, MZL, MALT lymphoma
Specimen Requirements
Bone Marrow Aspirate: 1-2mL Sodium Heparin Tube. EDTA tube is acceptable Peripheral Blood: 2-5mL Sodium Heparin Tube. EDTA tube is acceptable Fresh, Unfixed Tissue: Tissue in RPMI Bone Marrow/ Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: minimum 4 slides labeled with specimen type. Fluids: Equal parts RPMI to specimen volume. Fixed Cell Suspension: A client fixed cell suspension may be submitted for testing as long as it is received in 3:1 Methanol:Glacial Acetic Acid. Paraffin Block: H&E slide (required) plus paraffin block. Circle H&E for tech-only. Cut Slide: H&E slide (required) plus 8 unstained slides cut at 4 microns for panel. Circle H&E for tech-only. Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Storage and Transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
CPT Code(s)*
88374x4 automated. Codes may differ if manual analysis is performed.Â
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: January 22, 2025