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HER2 (Other)
- FISH
The HER2 (Other) FISH test is used to provide HER2 amplification status to aid in determining anti-HER2 targeted therapies for various tumor types.
Probes: HER2 (17q11.2-q12) | Centromere 17 (Cen 17)
Disease(s): Endometrial cancer, salivary duct carcinoma, ovarian cancer, serous carcinomas, and other various tumor types
Probes: HER2 (17q11.2-q12) | Centromere 17 (Cen 17)
Disease(s): Endometrial cancer, salivary duct carcinoma, ovarian cancer, serous carcinomas, and other various tumor types
Specimen Requirements
Pathology Report: For global HER2 FISH cases we require a copy of the HER2 IHC pathology report (if it is not available to us in NeoLINK„¢). For HER2 (Other) with Breast Scoring, the HER2 IHC slide may also be required for intrepation of results. Client Services will call your office or lab for missing IHC reports or to request slides.
Bone Marrow Aspirate: N/A
Peripheral Blood: N/A
Fresh, Unfixed Tissue: N/A
Fluids: N/A
Paraffin Block: H&E slide (required) plus paraffin block. Circle H&E for tech-only.
Cut Slides: H&E slide (required) plus 2 unstained slides cut at 4 microns.Circle H&E for tech only.
Storage and Transportation
For global HER2 FISH cases we require a copy of the HER2 IHC pathology report. NYS clients please provide date and time of Collection.
CPT Code(s)*
88374x1 automated. Codes may differ if manual analysis is performed.
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Biomarkers
Fluorescence In Situ Hybridization (FISH)
| Amplification(s) | |||||
|---|---|---|---|---|---|
| ERBB2 | |||||
Last Updated: January 28, 2026