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High-Grade B-Cell Lymphoma with 11q Aberration (formerly 11q Aberration in NHL)
- FISH
Clinical Significance
This FISH panel is designed to detect the recurrent proximal gains and distal losses of chromosome 11q which define MYC-negative high grade B-cell lymphoma with 11q aberration in WHO-HAEM5 and in the ICC-2022 (provisional).
Specimen Requirements
H&E slide (required) plus paraffin block.
Cut Slides: H&E slide (required) plus 3 unstained slides cut at 4-5 microns.
Note for Tech Only clients: Please circle H&E slide.
Storage and Transportation
Refrigerate specimen. Do not freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of collection.
CPT Code(s)*
88374x1 automated or 88377x1 manual
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Biomarkers
Fluorescence In Situ Hybridization (FISH)
| Rearrangement(s) | |||||
|---|---|---|---|---|---|
| 11q | |||||
Last Updated: February 18, 2026