Get in touch
Our Client Services team is on hand to help. Please call us at 866.776.5907, Option 3.
ALL Pediatric FISH Panel
- FISH
This FISH panel is designed to detect key genetic abnormalities associated with B-cell acute lymphoblastic leukemia (B-ALL) and B lymphoblastic lymphoma (LBL) in pediatric patients. Identification of specific abnormalities helps predict disease aggressiveness and response to therapy.
TCF3/PBX1 (E2A/PBX1) t(1;19)
Trisomy or Tetrasomy 4, 6, 10, 17 (Cen 4, Cen 6, Cen 10, Cen 17)
MYC (8q24)
BCR/ABL1/ASS1 t(9;22)
MLL (11q23)
ETV6/RUNX1 (TEL/AML1) t(12;21)
IgH (14q32)
Test Customization: Probes may be ordered separately, except that Centromeres 4 and 17 are paired, as are Centromeres 6 and 10. CDKN2A (p16) deletion testing is available to be ordered separately.
STAT Processing (upon request): Available for BCR/ABL1/ASS1 t(9;22). Include "STAT" along with the requesting physician's name and contact information for expedited results.
Specimen Requirements
Bone Marrow Aspirate: 1-2 mL in sodium heparin tube. EDTA tube is acceptable.
Peripheral Blood: 2-5 mL in sodium heparin tube. EDTA tube is acceptable.
Fresh, Unfixed Tissue: Tissue in RPMI.
Bone Marrow/Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: Minimum 8 slides, labeled with specimen type.
Fluids: Mix in equal parts with RPMI (specimen volume to RPMI ratio of 1:1).
Fixed Cell Suspension: A client-prepared fixed cell suspension is acceptable if received in 3:1 Methanol:Glacial Acetic Acid.
Storage and Transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. For fresh samples: refrigerate before shipping and ship same day as drawn whenever possible. Do not freeze. NYS clients please provide date and time of Collection.
CPT Code(s)*
88374x8 automated. Codes may differ if manual analysis is performed.
*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.
Last Updated: August 05, 2025