Ploidy FISH for Molar Pregnancy

FISH

Ploidy FISH analyzes centromeres 1 and 11 to assess triploidy (associated with partial mole) vs. diploidy (associated with complete mole).

Probes: Centromere 1 (1p11.1-q11.1) | Centromere 11 (11q12)
Antibody Marker: p57
Disease(s): Complete molar pregnancy vs. partial mole vs. abortus with hydropic changes
This test is available on a consult basis only.

Specimen Requirements

Bone Marrow Aspirate: N/A Peripheral Blood: N/A Fresh, Unfixed Tissue: N/A Paraffin Block: H&E slide (required) plus paraffin block. Cut Slides: H&E slide (required) plus 4 unstained slides cut at 4-5 microns. Note: Specimen must contain villi and/or fetal tissue.

Storage and Transportation

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

CPT Code(s)*

88377x1 manual or 88374x1 automated

Turnaround time

3-5 Days

Level of Service

Global

Integrations

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New York Approved: Yes

*The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.

Biomarkers

Fluorescence In Situ Hybridization (FISH)

Polyploidy
Centromere 1	Centromere 11

Last Updated: March 02, 2026

Get in touch

Our Client Services team is on hand to help. Please call us at 866.776.5907, Option 3.