NeoTYPE Cancer Profiles

NeoTYPE™ Cancer Profiles are multi-method test panels, custom-designed for a specific tumor type, that identify the genetic changes most significant to therapy decisions, prognosis, and clinical research. Read more.

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Methodology Test Name Test Description Print View
NeoTYPE Cancer Profiles NeoTYPE™ AML Prognostic Profile Bi-directional sequencing and mutation analysis of select exons of the following genes: CEBPA, DNMT3A, FLT3, IDH1, IDH2, NPM1, RUNX1, and WT1. Fragment analysis is performed on select genes for enhanced detection of low levels of insertion/deletion mutations. Testing can be performed on plasma for increased sensitivity when adequate leukemic cells are not available. This Profile may be ordered separately or as part of the AML Reflex Panel. View
NeoTYPE Cancer Profiles NeoTYPE™ Breast Tumor Profile Concurrent HER2 FISH, PTEN FISH, and bi-directional sequencing with mutation analysis of the following genes: BRAF, c-KIT, EGFR, PIK3CA, PTEN, and TP53. View
NeoTYPE Cancer Profiles NeoTYPE™ CLL Prognostic Profile

Concurrent analysis of ZAP-70 by flow cytometry, CLL-related chromosome abnormalities by FISH, and mutations of the IgVH, NOTCH1, and SF3B1 genes by bi-directional sequencing. Results are issued together in a comprehensive report.

Read more about the NeoTYPE™ CLL Prognostic Profile.

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NeoTYPE Cancer Profiles NeoTYPE™ Colorectal Tumor Profile Concurrent microsatellite instability analysis by PCR/fragment analysis, PTEN FISH, and bi-directional sequencing with mutation analysis of the following genes: BRAF, c-KIT, DNMT3A, EGFR, IDH1, IDH2, KRAS, NRAS, PIK3CA, PTEN, and TP53. View
NeoTYPE Cancer Profiles NeoTYPE™ Gastric Tumor Profile Concurrent HER2 FISH, PTEN FISH, and bi-directional sequencing with mutation analysis of the following genes: BRAF, c-KIT, DNMT3A, EGFR, IDH1, IDH2, KRAS, NRAS, PIK3CA, PTEN, and TP53. View
NeoTYPE Cancer Profiles NeoTYPE™ Lung Tumor Profile Concurrent ALK FISH, PTEN FISH, and bi-directional sequencing with mutation analysis of the following genes: BRAF, c-KIT, DNMT3A, EGFR, IDH1, IDH2, KRAS, NRAS, PIK3CA, PTEN, and TP53. View
NeoTYPE Cancer Profiles NeoTYPE™ Lymphoma Profile Concurrent molecular analyses of CCND1 (BCL1) t(11;14), BCL2 t(14;18), and bi-directional sequencing of select exons of CARD11, CD79B, MYD88, and TP53. BCL1 and BCL2 results are reported quantitatively when positive. Tests may be ordered separately. View
NeoTYPE Cancer Profiles NeoTYPE™ MDS/CMML Profile Concurrent bi-directional sequencing of select exons of the following 14 genes: ASXL1, CBL, EZH2, IDH1, IDH2, NRAS, PTPN11, RUNX1, SF3B1, SRSF2, TET2, TP53, U2AF1, and ZRSR2. Custom panels are available by request. View
NeoTYPE Cancer Profiles NeoTYPE™ Solid Tumor (Other) Profile Concurrent PTEN FISH and bi-directional sequencing with mutation analysis of the following genes: BRAF, c-KIT, DNMT3A, EGFR, IDH1, IDH2, KRAS, NRAS, PIK3CA, PTEN, and TP53. View
NeoTYPE Cancer Profiles NeoTYPE™ Spliceosome Mutation Profile Concurrent bi-directional sequencing of select exons of the following four genes: SF3B1, SRSF2, U2AF1 (also known as U2AF35), and ZRSR2. Tests are also available individually and as part of the NeoTYPE™ MDS/CMML Profile. View