NeoTYPE Cancer Profiles

NeoTYPE™ Cancer Profiles are multi-method test panels, custom-designed for a specific tumor type, that identify the genetic changes most significant to therapy decisions, prognosis, and clinical research. Read more.


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Methodology Test Name Test Description Print View
NeoTYPE Cancer Profiles NeoTYPE™ AML Favorable-Risk Profile This test is performed by bidirectional sequencing of select exons of the genes listed. Comprehensive Profile includes: FLT3, KIT. Test orders include summary interpretation of all results together. No Concise Profile is available; instead, order tests individually; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ AML Prognostic Profile This test is performed by bidirectional sequencing of select exons of the genes listed. Concise Profile includes: CEBPA, DNMT3A, FLT3, IDH1, IDH2, NPM1, NRAS. Comprehensive Profile includes added: ASXL1, PTPN11, RUNX1, TET2, TP53, WT1. Test orders include summary interpretation of all results together. Any tests may be ordered separately; these will be reported individually without summary interpretation. The AML Prognostic Profile may also be ordered as reflex after intermediate cytogenetics in the AML Reflex Panel (see separate AML Reflex Panel listing). View
NeoTYPE Cancer Profiles NeoTYPE™ Brain Tumor Profile This test is performed by bidirectional sequencing of select exons of the genes listed unless another method is noted. Concise Profile includes: BRAF, IDH1, IDH2, MGMT Promoter Methylation, 1p/19q Deletion FISH. Comprehensive Profile includes added: EGFR, PIK3CA, PTEN, TP53, PTEN FISH. Test orders include summary interpretation of all results together. Molecular-only test options are available for the Comprehensive and Concise Profiles. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ Breast Tumor Profile This test is performed by bidirectional sequencing of select exons of the genes listed unless another method is noted. Concise Profile includes: BRAF, EGFR, KIT, PIK3CA, PTEN, HER2 FISH, PTEN FISH. Comprehensive Profile includes added: TP53. Test orders include summary interpretation of all results together. Molecular-only test options are available for the Comprehensive and Concise Profiles. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ Cervical Tumor Profile This test is performed by bidirectional sequencing of select exons of the genes listed unless another method is noted. Concise Profile includes: BRAF, NOTCH1, PIK3CA, PTEN, PTEN FISH. Comprehensive Profile includes added: DNMT3A, HRAS, KRAS, NRAS, TP53. Test orders include summary interpretation of all results together. Molecular-only test options are available for the Comprehensive and Concise Profiles. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ CLL Prognostic Profile

This test is performed by bidirectional sequencing of select exons of the genes listed, plus the CLL FISH Panel and ZAP-70 flow cytometry as noted. Concise Profile includes: IgVH, NOTCH1, SF3B1, CLL FISH. Comprehensive Profile includes added: ZAP-70 flow. Test orders include summary interpretation of all results together. Molecular-only test options are available for the Comprehensive and Concise Profiles. Any tests may be ordered separately; these will be reported individually without summary interpretation.

Read more about the NeoTYPE™ CLL Prognostic Profile.

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NeoTYPE Cancer Profiles NeoTYPE™ Colorectal Tumor Profile This test is performed by bidirectional sequencing of select exons of the genes listed unless another method is noted. Concise Profile includes: BRAF, EGFR, KIT, KRAS, Microsatellite Instability by PCR/fragment anlaysis, MLH1 Promoter Methylation, PIK3CA, PTEN, PTEN FISH. Comprehensive Profile includes added: CSF3R, DNMT3A, NOTCH1, NRAS, PDGFRA, TP53. Test orders include summary interpretation of all results together. Molecular-only test options are available for the Comprehensive and Concise Profiles. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ Endometrial Tumor Profile This test is performed by bidirectional sequencing of select exons of the genes listed unless another method is noted. Concise Profile includes: EGFR, Microsatellite Instability by PCR/fragment analysis, PIK3CA, PTEN, PTEN FISH, interpretation. Comprehensive Profile includes added: KRAS, NRAS, PTPN11, TET2, TP53. Test orders include summary interpretation of all results together. Molecular-only test options are available for the Comprehensive and Concise Profiles. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ Esophageal Tumor Profile This test is performed by bidirectional sequencing of select exons of the genes listed unless another method is noted. Concise Profile includes: BRAF, KIT, KRAS, NOTCH1, PDGFRA, PIK3CA, PTEN, HER2 FISH, PTEN FISH. Comprehensive Profile includes added: CARD11, HRAS, NRAS, TP53. Test orders include summary interpretation of all results together. Molecular-only test options are available for the Comprehensive and Concise Profiles. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ Gastric Tumor Profile This test is performed by bidirectional Sanger sequencing of select exons of the genes listed unless another method is noted. Concise Profile includes: BRAF, EGFR, KIT, KRAS, NOTCH1, PDGFRA, PIK3CA, PTEN, HER2 FISH, PTEN FISH. Comprehensive Profile includes added: HRAS, NRAS, TP53. Test orders include summary interpretation of all results together. Molecular-only test options are available for the Comprehensive and Concise Profiles. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ GIST Profile This test is performed by bidirectional sequencing of select exons of the genes listed. Concise Profile includes: KIT, PDGFRA. Comprehensive Profile includes added: BRAF. Test orders include summary interpretation of all results together. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ JMML Profile This test is performed by bidirectional sequencing of select exons of the genes listed. Concise Profile includes: CBL, PTPN11. Comprehensive Profile includes added: KRAS, NRAS. Test orders include summary interpretation of all results together. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ Lung Tumor Profile TEMPORARY NOTICE regarding the Comprehensive Profile: RET FISH is temporarily unavailable.
The NeoTYPE Lung Tumor Profile is performed by bidirectional sequencing of select exons of the genes listed unless another method is noted. Concise Profile includes: BRAF, EGFR, KRAS, PIK3CA, ALK FISH, ROS1 FISH. Comprehensive Profile includes added: ASXL1, DNMT3A, EZH2, KIT, NOTCH1, NRAS, PDGFRA, PTEN, TP53, PTEN FISH, RET FISH. Test orders include summary interpretation of all results together. Molecular-only test options are available for the Comprehensive and Concise Profiles. Any tests may be ordered separately; these will be reported individually without summary interpretation.
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NeoTYPE Cancer Profiles NeoTYPE™ Lymphoma Profile This test is performed by bidirectional sequencing of select exons of the genes listed. Concise Profile includes: CARD11, CD79B, EZH2, MYD88. Comprehensive Profile includes added: BCL1, BCL2. Test orders include summary interpretation of all results together. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ MDS/CMML Profile This test is performed by bidirectional sequencing of select exons of the genes listed. Concise Profile includes: ASXL1, CBL, ETV6, EZH2, IDH1, IDH2, NRAS, RUNX1, SF3B1, SRSF2, TET2, TP53. Comprehensive Profile includes added: DNMT3A, PTPN11, U2AF1, ZRSR2. Test orders include summary interpretation of all results together. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ Melanoma Profile This test is performed by bidirectional sequencing of select exons of the genes listed. Concise Profile includes: BRAF, KIT. Comprehensive Profile includes added: NRAS. Test orders include summary interpretation of all results together. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ MPN Profile This test is performed by bidirectional sequencing of select exons of the genes listed. Concise Profile includes: ASXL1, CALR, EZH2, JAK2 V617F, MPL, TET2. Comprehensive Profile includes added: CSF3R, JAK2 EXON 12-14, PTPN11, SRSF2, U2AF1. Test orders include summary interpretation of all results together. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ Other Solid Tumor Profile This test is performed by bidirectional sequencing of select exons of the genes listed unless another method is noted. Concise Profile includes: BRAF, EGFR, KIT, KRAS, NOTCH1, NRAS, PDGFRA, PIK3CA, PTEN, PTEN FISH. Comprehensive Profile includes added: ASXL1, DNMT3A, EZH2, GNAS, HRAS, IDH1, IDH2, PTPN11, TET2, TP53. Test orders include summary interpretation of all results together. Molecular-only test options are available for the Comprehensive and Concise Profiles. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ Ovarian Tumor Profile This test is performed by bidirectional sequencing of select exons of the genes listed unless another method is noted. Concise Profile includes: BRAF, PIK3CA, PTEN, SNP Array, PTEN FISH. Comprehensive Profile includes added: HRAS, KRAS, NRAS, TP53. Test orders include summary interpretation of all results together. Molecular-only test options are available for the Comprehensive and Concise Profiles. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ Soft Tissue Tumor Profile This test is performed by bidirectional sequencing of select exons of the genes listed unless another method is noted. Concise Profile includes: BRAF, KIT, PDGFRA, PIK3CA, PTEN, PTEN FISH. Comprehensive Profile includes added: GNAS, HRAS, KRAS, NRAS, TP53. Test orders include summary interpretation of all results together. Molecular-only test options are available for the Comprehensive and Concise Profiles. Any tests may be ordered separately; these will be reported individually without summary interpretation. View
NeoTYPE Cancer Profiles NeoTYPE™ Spliceosome Mutation Profile This test is performed by bidirectional sequencing of select exons of the genes listed. Comprehensive Profile includes: SF3B1, SRSF2, U2AF1, ZRSR2. Test orders include summary interpretation of all results together. No Concise Profile is available; instead, tests may be ordered individually; these will be reported individually without summary interpretation. View